{"id":3665,"date":"2021-05-10T09:53:00","date_gmt":"2021-05-10T09:53:00","guid":{"rendered":"https:\/\/www.fuerstenmahl.li\/?p=3665"},"modified":"2023-11-06T07:44:49","modified_gmt":"2023-11-06T07:44:49","slug":"3665-2","status":"publish","type":"post","link":"https:\/\/www.fuerstenmahl.li\/en\/3665-2","title":{"rendered":"COVID-19 Langzeitfolgen"},"content":{"rendered":"<p><a href=\"Editorial: The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and the Role of Microglia, Mitochondria, and Persistent Neuroinflammation.\"><em>Editorial: The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and the Role of Microglia, Mitochondria, and Persistent Neuroinflammation.<\/em><\/a><\/p><p>Persistent comorbidities occur in patients who initially recover from acute coronavirus disease 2019 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34016942\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34016942\/<\/a>(COVID-19) due to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). \u2018Long COVID\u2019 involves the central nervous system (CNS), resulting in neuropsychiatric symptoms and signs, including cognitive impairment or \u2018brain fog\u2019 and chronic fatigue syndrome. There are similarities in these persistent complications between SARS-CoV-2 and the Ebola, Zika, and influenza A viruses. Normal CNS neuronal mitochondrial function requires high oxygen levels for oxidative phosphorylation and ATP production. Recent studies have shown that the SARS-CoV-2 virus can hijack mitochondrial function. Persistent changes in cognitive functioning have also been reported with other viral infections. SARS-CoV-2 infection may result in long-term effects on immune processes within the CNS by causing microglial dysfunction. This short opinion aims to discuss the hypothesis that the pathogenesis of long-term neuropsychiatric COVID-19 involves microglia, mitochondria, and persistent neuroinflammation.<\/p><p>Stefano GB, B\u00fcttiker P, Weissenberger S, Martin A, Ptacek R, Kream RM. Editorial: The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and the Role of Microglia, Mitochondria, and Persistent Neuroinflammation: A Hypothesis. Med Sci Monit. 2021 May 10;27:e933015.<\/p><p><a href=\"https:\/\/medscimonit.com\/abstract\/full\/idArt\/933015\">https:\/\/medscimonit.com\/abstract\/full\/idArt\/933015<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Editorial: The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and the Role of Microglia, Mitochondria, and Persistent Neuroinflammation. Persistent comorbidities occur in patients who initially recover from acute coronavirus disease 2019 https:\/\/pubmed.ncbi.nlm.nih.gov\/34016942\/(COVID-19) due to infection with severe &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"COVID-19 Langzeitfolgen\" class=\"read-more button\" href=\"https:\/\/www.fuerstenmahl.li\/en\/3665-2#more-3665\">Weiterlesen<span class=\"screen-reader-text\">COVID-19 Langzeitfolgen<\/span><\/a><\/p>","protected":false},"author":29,"featured_media":3666,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3665","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>COVID-19 Langzeitfolgen - F\u00fcrstenmahl<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fuerstenmahl.li\/en\/3665-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"COVID-19 Langzeitfolgen - F\u00fcrstenmahl\" \/>\n<meta property=\"og:description\" content=\"Editorial: The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and the Role of Microglia, Mitochondria, and Persistent Neuroinflammation. Persistent comorbidities occur in patients who initially recover from acute coronavirus disease 2019 https:\/\/pubmed.ncbi.nlm.nih.gov\/34016942\/(COVID-19) due to infection with severe ... 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